My last dexa scan (summer of 2011) indicated that there had not been any decline in my bone density. Recently I developed chronic diarrhea. I also often add a handful of organic nuts (walnuts, pumpkin seeds, pine nuts, almonds, cashews, pecansetc.) He asked me to take for 6 months this Strontium Renalate suspension every year. The study to which you sent me a link is the only human study I could find, but recent papers indicate lactoferrin may be quite helpful. 2012 Jul;51(1):93-7. ) The researchers hypothesized that strontium like calcium may activate a calcium-sensing receptor on breast cells that increases the expression of estrogen receptors, and thus have an estrogen-like effect. You can, of course, purchase boron separately (and have to open yet another bottle and take yet another pill every day), but I, personally, just rely on AlgaeCal Plus, which contains not only the calcium our bones require, but also the 3 milligrams of boron, plus magnesium and vitamin D3. It's not known if strontium. A creatinine clearance rate of 60-89 indicates the initial stage of kidney disease. For example, taking some medicines at the same time as eating may prevent your stomach and intestines absorbing the medicine, making it less effective. It is ALWAYS best to trust yourself. Some medicines need to be taken "before food" or "on an empty stomach". The MK-4 that I take is such a small dose, that should be OK, right . Strontium Ranelate has a long list of adverse side-effects, starting with common ones like: And less common, but possibly deadly effects like: Overall, the likelihood that you will be among the ones affected may be small although a review of the research on strontium ranelate published in 2005 states Strontium [ranelate] caused a 50% increase in the risk of venous thromboembolism (including pulmonary embolism).. Laboratoire dHistodynamique Osseuse, Facult de Mdecine R. Laennec, 69372, Lyon Cedex 08, France. Stable strontium itself has never been found to cause any harmful effects with one caveat: to maintain proper balance between calcium and strontium, more calcium than strontium must be consumed. Equating them is like suggesting sodium chloride (table salt) and sodium bicarbonate (baking powder) are the same. I have family sisters with ckd. Virtually all minerals must combine with another organic compound to be stable (e.g., citrate, malate, chloride) These stable compounds are referred to as salts. I take a few protein shakes to get the lactoferrin, eat mostly vegetarian (loved your navy bean receipe), try to keep urine in alkaline range. Unfortunately, we arent familiar with the safety of canned sardines for dogs. And so are my gluten-free sourdough breads you can find the recipes here (add link). That's why our formula contains over 12 different supplements in one. Thanks for looking and for your input. And we can check, in terms of our bones, whats happening with NTx and DXA tests, also our vitamin D levels, and Im hoping soon the test for vitamin K levels (its called unOC, which stands for uncarboxylated osteocalin) will be widely available. The fact that strontium ranelate may cause venous thromboembolism and DRESS syndrome (among other nasty effects) strongly suggests otherwise. Certainly worth bookmarking for revisiting. I wonder if the interval, between Calcium intakes is too short. It is best to take strontium supplements and calcium at different times of day to get the most benefit. I learned so much! Taking your thyroid medication properly helps you absorb it well and limits your risk of side effects. I heard it was not good to take it so long. What are her vitamin D levels her (25(OH)D blood levels? I REALLY want this to work so any insight you have would be gratefully received. Even at the highest dose of 255 mg Sr21/kg per day, the apatite crystals in the treated animals were intermediates between a physiologic calcium hydroxyapatite and an apatite where one calcium atom out of ten was substituted by a strontium atom. It has been suggested that bone resorption is most active at night, so taking strontium citrate just before bed may result in strontium exerting more of its antiresorptive effects when they are needed most. COMPETITION BETWEEN CALCIUM, STRONTIUM, AND MAGNESIUM FOR ABSORPTION IN THE ISOLATED RAT INTESTINE.Clin Chem. 5.0 out of 5 stars Bone Health. The end result was that more calcium (Ca2+) was deposited in AlgaeCal treated cells (2.0-fold more than controls, 1.0-fold more than calcium carbonate, and 4.0-fold more than calcium citrate-treated cells). Meunier, P. J., Roux, C., Seeman, E., Ortolani, S., Badurski, J. E., Spector, T. D., I started out taking just 1 capsule not because I wanted to take less than 680 mg of strontium but b/c I did not carefully read the label. Memorial Sloan Kettering Cancer Center. Do you have any recommendations before getting the scan as far as discontinuing either the algae cal or strontium or any other minerals or vitamins? John. Mechanisms of action and therapeutic potential of strontium in bone. But, once again, I have no idea of the amount of additional calcium that is entering my body. Alternatively, some foods can interact with . Teenagers 14-18 years: 15 micrograms (600 IU) This is the dose that has been used in almost all the human research conducted on stable strontium salts. The drug makes your bones stronger and lowers your chances of getting fractures. Marilyn, Sorry, used to the post preview at NOH, lots of booboos! Seemingly in Europe every time they move wheat from country to country they spray it with insecticide and of course you can imagine what that does to your system. You are so welcome! So interesting! Here are a couple of the most recent: Angle SR, Sena K, Sumner DR, Virdi AS. However, I believe my gains in BMD would have been even greater had I been consistently taking the strontium. Strontium increases the production of osteocalcin Thanks, delighted you have found the blogs and Your Bones helpful. Both strontium citrate and bio-identical estrogen (likely bi-est) replacement will improve the health of your bones. My concern is that if Strontium Citrate is a salt will it raise my blood pressure? This one really shouldn't . Can this be whats going on? Hi, Elena! I live in Arizona, but lungs keep me inside mostly as air here is dry and very dusty. Vitamin D increases our bodys ability to absorb calcium; vitamin K2 activates the proteins responsible for putting calcium into bone (osteocalcin) and keeping it OUT of arteries, kidneys, breasts. However, no research that I know of specifically shows that 170 mg of strontium /day is more effective in preventing fracture risk, and the only PubMed article I can find for Meunier et al in 2002 concludes a 2 gram/day dose is most effective here is the abstract: Pors Nielsen S. The biological role of strontium. Both strontium and citrate are natural substances that are highly beneficial to and are utilized within the body ideally, the majority of the strontium in strontium citrate supplements is absorbed into bone, increasing bone mass and strength. 2. Do I continue to take my Viactive calcium chew and my I-cap multiple vitamins with the Algaecal and Strontium ? I sent the following reply to one of them to share there: I found the discussion and have been looking and looking and looking for any research showing strontium citrate is toxic. I am not familiar with the quality control standards held by Drs Best you might want to check with them to learn what tests are run to ensure their products are free of contaminants, etc. Since the most current research indicates that half the typical dose of strontium (i.e., one capsule of Strontium Boost daily rather than two) is helpful, start out taking just one capsule daily at night please, at least 4 hours after you take your PM dose of AlgaeCal Plus since night time consumption of strontium citrate has been found most effective. Yes, your DXA BMD score will be impacted by strontium. That said, we understand everyone is unique and we want to ensure youre feeling your best! This is why you want to be sure to be consuming twice as much calcium (from diet and supplements combined) as strontium. Taking strontium supplements for any period of time is likely to make future bone density tests inaccurate. the only Ca complex to increase bone density in adults! I take 1800 IU of Calcium daily (I will switch to Calcium Citrate since I have been taking the Calcium Carbonate chews and with meds for Acid Reflux I guess this was the wrong type of calcium for me) I also take Vit B12 250 mcg, Vitamin D 2200 IU and Omega 3 Fish oil 1000 mg. Epub 2004 Sep 13. That a chronic infection might promote bone loss makes a lot of sense. A. The ability of this IVXRF system to monitor and measure bone strontium levels over time provides a useful diagnostic tool to help gain insight into strontium bone kinetics. So, Im writing you directly with a brief summary of some of the relevant information provided in my update on strontium, which I hope will allay your concerns. I remember when my mother was dying from hip fracture + congestive heart failure along with my 23 year old cat, who we were giving fluids several times a day because of her kidney failure I was so stressed out and sad that I lost TONS of hair. I am concerned because I want to understand my osteoporosis treatment and make sure it meets your recommendations (like taking twice as much calcium as strontium possibly 1360 mg? Subjects were 160 postmenopausal women, mean age 73 years, with a hip BMD value of more than 2 standard deviations below the reference value, so clearly well into the osteopenic / osteoporotic range. Farah, Hi Farah, When availableas now in our gardenI top my raw greens salad with some fresh blueberries. Hello Cinzia, But, after reading all the current research (more than 70 papers) on strontium, I started taking it again at a half dose to ensure my bones remain healthy. In fact, each has harmful side effects. activate vitamin D (vitamin D is converted into its active, hormonal form which is the form in which vitamin D helps us absorb calcium from the digestive tractin the kidneys) 2005 Mar;20(3):548. topic. Hi Dianne, thanks for sharing and reaching out! Some researcher believe that calcium and magnesium, being 2 cation molecules, should be taken separately for optimal absorption of both minerals. In more than 100 years of research on strontium, including a number of recent human studies discussed below, no adverse effects have been reported for any natural stable strontium salt when more calcium than strontium is consumed. Thank You for this well-written, researched, and easy-to-understand article. 10. The issue is not bone mineral density, but the bodys exposure to estrogens when they are being metabolized into pro-inflammatory, potentially carcinogenic derivatives. Detailed analysis indicates that many transporters (such as PepT1, SGLT-1, GLUT5, MRP2, NT2, and high affinity glutamate transporter) share similar expression levels in both human and rat with regional dependent expression patterns, which have high expression in the small intestine and low expression in the colon. Who wrote this article? Venous thromboembolism (VTE) refers to life-threatening blood clots in deep veins. As you know, our bones continue to remodel throughout our lives, so the therapies used to support healthy bones must be ones we can rely on long-term. Metabolism 2002;51:906 11. Take three (3) capsules once daily, or as recommended by a healthcare practitioner. Were here for any questions! Vit D3 increases your bodys production of vit K dependent proteins, so you will make more of them and will need more K2 to activate them. There are a number of important to me differences between the algae used in New Chapter Bone Strength Take Care (Aquamin) and that which is used for AlgaeCal (Algas calcareus). As a result, about 5% of dialysis patients develop osteomalacia (softening of the bones). Am insurance poor, so have to go to conventional doctors. Hi Lara: Clearly, anyone with severe osteoporosis should work with a well qualified physiotherapist, and my preference would be the use of a highly supportive and very safe exercise regimen like Pilates which has also been shown to be able to target and help build specific areas of bone until bone density was restored to the osteopenic level. The very tiny amount of strontium ions that deposit in our bones prefer to do so in trabecular, not cortical bone. All my love Linda. I follow the Bresdan protocol, eat a whole foods Keto diet, am gluten,dairy,soy and sugar free, walk 3 miles daily, and eat organic 90% of the time. I do have low bone density in my spine (-2.5 T score) and also in my hips (-3.3 on one side, -3.0 on the other) so am pretty concerned at this point. What is the excretion of strontium citrate? I am under a functional medical doctor and nutritionist, but wanted to tap into your expertise as well. Rely on Science, not rumor. Both minerals share a common carrier system in the intestinal wall, which will always choose to transport calcium rather than strontium from our digestive tract into our bloodstream. Hi Kay, I would really appreciate hearing from you before I place an order for the AlgaeCal Plus and possibly, their Strontium Boost. https://www.nejm.org/doi/full/10.1056/NEJMoa1408913, And the incidence of C. difficile infection has been increasing every year. Lots of booboos Arizona, but lungs keep me inside mostly as here! Deep veins walnuts, pumpkin seeds, pine nuts, almonds, cashews pecansetc! Very dusty link ) however, i have no idea of the amount of strontium ions that in... 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